Presentation Title

Quantification and Correlation of 4-Nonylpehnol in the Human Body via Urinalysis and the Environment through Enzyme Linked Immunosorbent Assay, Gas, and Liquid Chromatography Mass Spectroscopy

Start Date

November 2016

End Date

November 2016

Location

HUB 302-10

Type of Presentation

Poster

Abstract

Modern farming techniques and the ever increasing demand for food by a growing population has led to the increased usage of pesticides. Nonylphenol ethoxylates, a surfactant, composing up to 10% by weight of many pesticides. These compounds undergo bacterial degradation leading to the formation of nonylphenol, an estrogen mimic which can be absorbed into the human body. This study investigates one of the major branched isomers of nonylphenol, 4-nonphenol (4-NP), a compound linked to the proliferation of cancer cells at high exposure concentrations. Analysis by ELISA, GC/MS, and LC/MS for 4-NP in several Southern California lakes have been performed in order to determine regions with high and low exposure risk. Human urine samples were used to determine the concentration of 4-nonylphenol in adjacent populations. Correlations were determined between the human urine concentrations and environmental concentrations.

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Nov 12th, 1:00 PM Nov 12th, 2:00 PM

Quantification and Correlation of 4-Nonylpehnol in the Human Body via Urinalysis and the Environment through Enzyme Linked Immunosorbent Assay, Gas, and Liquid Chromatography Mass Spectroscopy

HUB 302-10

Modern farming techniques and the ever increasing demand for food by a growing population has led to the increased usage of pesticides. Nonylphenol ethoxylates, a surfactant, composing up to 10% by weight of many pesticides. These compounds undergo bacterial degradation leading to the formation of nonylphenol, an estrogen mimic which can be absorbed into the human body. This study investigates one of the major branched isomers of nonylphenol, 4-nonphenol (4-NP), a compound linked to the proliferation of cancer cells at high exposure concentrations. Analysis by ELISA, GC/MS, and LC/MS for 4-NP in several Southern California lakes have been performed in order to determine regions with high and low exposure risk. Human urine samples were used to determine the concentration of 4-nonylphenol in adjacent populations. Correlations were determined between the human urine concentrations and environmental concentrations.