Presentation Title

A 3D-printed, Microfluidic Device for Alginate Microbead Synthesis

Start Date

November 2016

End Date

November 2016

Location

HUB 302-79

Type of Presentation

Poster

Abstract

The biocompatibility of alginate hydrogels makes it a viable candidate for various applications such as stem cell culture and growth factor delivery. Droplet microfluidics allows the generation of microbeads of a size ranging from tens to hundreds of micrometers in diameter. The goal of this study is to design a microfluidic device suitable for continuously producing alginate microbeads of uniform shape and size. We designed a cylindrical microfluidic chip using SketchUp and 3D-printed it with a commercial acrylic resin using the digital light processing (DLP) technology. At a flow ratio of 1 to 10 (alginate solution vs. oil), we successfully synthesized alginate microbeads of 577.19 ± 5.46 μm in diameter in a manually controlled, continuous process. We are developing a new controller for process automation with open-source electronics and Python.

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Nov 12th, 1:00 PM Nov 12th, 2:00 PM

A 3D-printed, Microfluidic Device for Alginate Microbead Synthesis

HUB 302-79

The biocompatibility of alginate hydrogels makes it a viable candidate for various applications such as stem cell culture and growth factor delivery. Droplet microfluidics allows the generation of microbeads of a size ranging from tens to hundreds of micrometers in diameter. The goal of this study is to design a microfluidic device suitable for continuously producing alginate microbeads of uniform shape and size. We designed a cylindrical microfluidic chip using SketchUp and 3D-printed it with a commercial acrylic resin using the digital light processing (DLP) technology. At a flow ratio of 1 to 10 (alginate solution vs. oil), we successfully synthesized alginate microbeads of 577.19 ± 5.46 μm in diameter in a manually controlled, continuous process. We are developing a new controller for process automation with open-source electronics and Python.