Presentation Title

“Unlocking the Glow in the Heart of the Ocean: Medical Advancements using Bioluminescence Imaging”

Presenter Information

Bethany SestiFollow

Faculty Mentor

Kamran Golestaneh

Start Date

17-11-2018 12:30 PM

End Date

17-11-2018 2:30 PM

Location

HARBESON 35

Session

POSTER 2

Type of Presentation

Poster

Subject Area

health_nutrition_clinical_science

Abstract

Bioluminescent imaging allows early discovery of cancers, diseases, and the viability of medication which is crucial in modern health care. Cancer is the second leading cause of death worldwide and researching viable treatments is paramount. Bioluminescent imaging is a noninvasive, scientific breakthrough providing precise diagnostic results from luminescent markers. Scientists have not conducted this imaging on humans. However, tests on rodents have resulted in success. My approach encompassed several articles addressing the steps and technology making this imaging possible. The use of luciferin and luciferase in different diagnostic procedures allows a close look inside the body or on cells apart from the body. Bioluminescent imaging allows for a close look inside the body by modifying the chemical compound Luciferin (which produces light) and the protein Luciferase (enabling light reaction to occur) extracted from bioluminescent organisms, such as fireflies or jellyfish. I discovered that when these components react with each other they emit light, detected by equipment capable of locating the accumulation of light. Also, scientists may inject the genes responsible for generating luciferase inside a virus which will then infect wanted cells for observation. The luciferase will be synthesized in the cells and will combine with the injected modified luciferin to emit light. There are no major implications that have been brought to scientist’s attention at this time. This type of imaging enables scientists and medical professionals to observe different biological processes. Furthering research in bioluminescent imaging can provide an advancement of detecting and accurately treating diseases in human individuals.

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Nov 17th, 12:30 PM Nov 17th, 2:30 PM

“Unlocking the Glow in the Heart of the Ocean: Medical Advancements using Bioluminescence Imaging”

HARBESON 35

Bioluminescent imaging allows early discovery of cancers, diseases, and the viability of medication which is crucial in modern health care. Cancer is the second leading cause of death worldwide and researching viable treatments is paramount. Bioluminescent imaging is a noninvasive, scientific breakthrough providing precise diagnostic results from luminescent markers. Scientists have not conducted this imaging on humans. However, tests on rodents have resulted in success. My approach encompassed several articles addressing the steps and technology making this imaging possible. The use of luciferin and luciferase in different diagnostic procedures allows a close look inside the body or on cells apart from the body. Bioluminescent imaging allows for a close look inside the body by modifying the chemical compound Luciferin (which produces light) and the protein Luciferase (enabling light reaction to occur) extracted from bioluminescent organisms, such as fireflies or jellyfish. I discovered that when these components react with each other they emit light, detected by equipment capable of locating the accumulation of light. Also, scientists may inject the genes responsible for generating luciferase inside a virus which will then infect wanted cells for observation. The luciferase will be synthesized in the cells and will combine with the injected modified luciferin to emit light. There are no major implications that have been brought to scientist’s attention at this time. This type of imaging enables scientists and medical professionals to observe different biological processes. Furthering research in bioluminescent imaging can provide an advancement of detecting and accurately treating diseases in human individuals.