Presentation Title

Hypochlorous acid Solution Treatment for Wound Healing

Faculty Mentor

Cord Brundage

Start Date

17-11-2018 8:30 AM

End Date

17-11-2018 10:30 AM

Location

CREVELING 19

Session

POSTER 1

Type of Presentation

Poster

Subject Area

biological_agricultural_sciences

Abstract

Hypochlorous acid (HA) is an electrically neutral oxidant available commercially in solutions as an antimicrobial wound treatment. We tested the effects of HA on wound healing, incidence of infection, and wound bacterial colonization in swine (Sus scrofa domesticus). The act of pig-ear-notching is an individual tagging system, used to distinguish animal numbers and litters. When notching, a small wedge of skin is removed at specific locations on one or both ears in piglets within 3 days following birth. These wounds usually resolve within 7-10 days without complications to the animals. In this double-blind study, three litters were used, totaling a piglet count of 18. Piglets received bilateral notching; both ears received the same number of notches in the same location, by the same individual. One ear was randomly treated with topical HA and the other treated with a topical control solution. Both ears were treated with their respective solutions immediately following ear notching as well as 3 and 7 days following ear notching. Photographs for notch wound scoring and inflammation grading, as well as infrared thermography (to evaluate areas of increased surface temperature/inflammation) were performed on days 1, 3, 7, and 10. Results provide evidence not only on the potency of HA as an inflammation preventative but also its activity expediting wound healing

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Nov 17th, 8:30 AM Nov 17th, 10:30 AM

Hypochlorous acid Solution Treatment for Wound Healing

CREVELING 19

Hypochlorous acid (HA) is an electrically neutral oxidant available commercially in solutions as an antimicrobial wound treatment. We tested the effects of HA on wound healing, incidence of infection, and wound bacterial colonization in swine (Sus scrofa domesticus). The act of pig-ear-notching is an individual tagging system, used to distinguish animal numbers and litters. When notching, a small wedge of skin is removed at specific locations on one or both ears in piglets within 3 days following birth. These wounds usually resolve within 7-10 days without complications to the animals. In this double-blind study, three litters were used, totaling a piglet count of 18. Piglets received bilateral notching; both ears received the same number of notches in the same location, by the same individual. One ear was randomly treated with topical HA and the other treated with a topical control solution. Both ears were treated with their respective solutions immediately following ear notching as well as 3 and 7 days following ear notching. Photographs for notch wound scoring and inflammation grading, as well as infrared thermography (to evaluate areas of increased surface temperature/inflammation) were performed on days 1, 3, 7, and 10. Results provide evidence not only on the potency of HA as an inflammation preventative but also its activity expediting wound healing