Presentation Title

The Perfect Bar of Soap for Grandpa: Eliminating The Odor Associated With The Elderly

Faculty Mentor

Asmik Oganesyan

Start Date

17-11-2018 8:00 AM

End Date

17-11-2018 8:15 AM

Location

C335

Session

Oral 1

Type of Presentation

Oral Talk

Subject Area

physical_mathematical_sciences

Abstract

2-trans-nonenal, the molecule often associated with the smell of the elderly, is produced increasingly in our bodies as we age. This unsaturated aldehyde is insoluble in water due to its hydrophobic structure, and cannot be removed with traditional soaps. Evidently, it leaves behind an unpleasant smell. Manufacturers of an expensive commercial soap made from persimmon extract hypothesized that the high concentration of tannins in persimmons traps the hydrophobic 2-trans-nonenal in their polyphenolic structure. The objective of this study was to synthesize tannin analogs and use natural ingredients which already have high concentrations in tannins to incorporate them into soaps that are suitable for aging skin. For preparation of synthetic analogs of tannins, different esterification reactions were performed. The products were analyzed by IR and NMR spectroscopy which confirmed the formation of the pure products. We further investigated the effects of tannins by formulating soaps with naturally-occurring ingredients, such as fruits and grains, containing high concentrations of tannins. A combinatorial approach was used to prepare a library of 343 different soaps with various oil, solid, and liquid additives. These soaps were then investigated for their conditioning, foaming, and cleansing properties, as well as for the ability to remove 2-trans-nonenal. The tests indicated that our soaps met the industrial quality standards and successfully reduced the smell of nonenal.

Summary of research results to be presented

For the soap formulation project, a combinatorial approach was used to produce 343 different soaps, each with different additives of high tannin concentration. A total of five soaps were isolated due to their success in the targeted properties: pH, hardness, cleansing, conditioning and lather. The final test of these five soaps focused on ultimately removing the smell of 2-trans-nonenal. Specific ingredients such as flax seeds, cantaloupe and lentils were amongst the top five candidates; concentrated in tannins and having great potential in the capture of a structure like 2-trans-nonenal. When tested on a scarf obtained from an estate sale, highly infused with the smell of 2-trans-nonenal, the odor was successfully removed. This was analyzed by comparing the IR spectra. The peaks of 2-trans-nonenal on the scarf before application were no longer present as determined by the second IR taken after a single wash with one of the five isolated soaps. Future work will focus on recreating this type of success on skin, and safe incorporation of the synthetic tannin analogs into these soaps. Similarly, we will explore more natural ingredients for improving the quality of the soap for the elderly.

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Nov 17th, 8:00 AM Nov 17th, 8:15 AM

The Perfect Bar of Soap for Grandpa: Eliminating The Odor Associated With The Elderly

C335

2-trans-nonenal, the molecule often associated with the smell of the elderly, is produced increasingly in our bodies as we age. This unsaturated aldehyde is insoluble in water due to its hydrophobic structure, and cannot be removed with traditional soaps. Evidently, it leaves behind an unpleasant smell. Manufacturers of an expensive commercial soap made from persimmon extract hypothesized that the high concentration of tannins in persimmons traps the hydrophobic 2-trans-nonenal in their polyphenolic structure. The objective of this study was to synthesize tannin analogs and use natural ingredients which already have high concentrations in tannins to incorporate them into soaps that are suitable for aging skin. For preparation of synthetic analogs of tannins, different esterification reactions were performed. The products were analyzed by IR and NMR spectroscopy which confirmed the formation of the pure products. We further investigated the effects of tannins by formulating soaps with naturally-occurring ingredients, such as fruits and grains, containing high concentrations of tannins. A combinatorial approach was used to prepare a library of 343 different soaps with various oil, solid, and liquid additives. These soaps were then investigated for their conditioning, foaming, and cleansing properties, as well as for the ability to remove 2-trans-nonenal. The tests indicated that our soaps met the industrial quality standards and successfully reduced the smell of nonenal.