Presentation Title

Identification and Annotation of Protein Orthology in Drosophila elegans

Presenter Information

Eduardo CruzFollow

Faculty Mentor

Alexa Sawa

Start Date

18-11-2017 12:30 PM

End Date

18-11-2017 1:30 PM

Location

BSC-Ursa Minor 68

Session

Poster 2

Type of Presentation

Poster

Subject Area

biological_agricultural_sciences

Abstract

Evaluation of possible genetic coding sequence conservation across two species of Drosophila using comparative genomics. Identification and subsequent annotation of conserved protein orthologues between D. melanogaster (Dmel) and D. elegans (Dele) was completed. Using Genscan software to identify possible coding sequences in a 60,000bp contig of Dele. Predicted coding genetic sequences were identified and screened using Flybase and Blastx software. Protein predictions with strong conservation to known proteins in Dmel were annotated using amino acid alignments constructed with NCBI Blast alignment tool. The results of these assessments strongly indicate evidence supporting that seven predicted proteins found in the contig of Dele are conserved orthologous found in Dmel. The research goal of this project is to further the understanding of conserved hetero-chromatin structure and phenotypic expression within the species of Drosophila.

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Nov 18th, 12:30 PM Nov 18th, 1:30 PM

Identification and Annotation of Protein Orthology in Drosophila elegans

BSC-Ursa Minor 68

Evaluation of possible genetic coding sequence conservation across two species of Drosophila using comparative genomics. Identification and subsequent annotation of conserved protein orthologues between D. melanogaster (Dmel) and D. elegans (Dele) was completed. Using Genscan software to identify possible coding sequences in a 60,000bp contig of Dele. Predicted coding genetic sequences were identified and screened using Flybase and Blastx software. Protein predictions with strong conservation to known proteins in Dmel were annotated using amino acid alignments constructed with NCBI Blast alignment tool. The results of these assessments strongly indicate evidence supporting that seven predicted proteins found in the contig of Dele are conserved orthologous found in Dmel. The research goal of this project is to further the understanding of conserved hetero-chromatin structure and phenotypic expression within the species of Drosophila.