Presentation Title

Photodegradation of Zidovudine in Wastewater Effluent treated via Anaerobic Baffled Reactor Technology

Faculty Mentor

Dr. Natalie Mladenov, Dr. Monica Palomo, Dr. Bice Martincigh, Chris Buckley, Bjoern Pietruschka

Start Date

18-11-2017 12:30 PM

End Date

18-11-2017 1:30 PM

Location

BSC-Ursa Minor 119

Session

Poster 2

Type of Presentation

Poster

Subject Area

engineering_computer_science

Abstract

Abstract: Increased use of pharmaceuticals over recent decades have led to vast improvements in health in many locations across the globe. Pharmaceuticals and personal care products (PPCPs) enter the environment through human consumption and excretion, hospital waste discharges, improper disposal of medicine, and incomplete removal at municipal wastewater treatment plants. Once present in the environment, PPCPs interact with other compounds and are influenced by natural conditions, such as sunlight. Anaerobic baffled reactor (ABR) technology is a decentralized wastewater treatment system (DEWATS) implemented in locations across the globe and is being studied for its viability for urban and peri-urban communities in South Africa for non-potable reuse. Studies were conducted on ABR effluent to isolate the effects of sunlight on the concentration of a common HIV antiretroviral (ARV) chemical, zidovudine (AZT), known to have photoactive functional groups. Water quality parameters, including pH, temperature, dissolved oxygen (DO) concentration, and conductivity, were monitored in unspiked samples and samples spiked with AZT. Each sample was also solid-phase extracted for subsequent liquid chromatography analyses. Results indicate that water quality remained consistent through the experiment, which signifies that other factors, such as a change in pH or DO, did not influence the experiment, and any changes in AZT concentration would be due to solar radiation alone. UV/VIS absorbance intensities were also measured, and results, as compared to UV data from standards of known concentrations of AZT, showed a decrease in AZT over the five hours. These results will supplement further analyses via fluorescence spectrometry, high performance liquid chromatography (HPLC) and liquid chromatography mass spectrometry (LC-MS) to isolate the phototransformation effects on AZT in ABR effluent. Results from this experiment will inform further studies necessary to understand how PPCPs are transformed in the environment.

Keywords: Pharmaceuticals and Personal Care Products (PPCPs), Contaminants of Emerging Concern (CECs), Anaerobic Baffled Reactor (ABR), Decentralized Wastewater Treatment (DEWATS), zidovudine or azidothymidine (AZT), photodegradation, South Africa, water treatment, sustainability

This document is currently not available here.

Share

COinS
 
Nov 18th, 12:30 PM Nov 18th, 1:30 PM

Photodegradation of Zidovudine in Wastewater Effluent treated via Anaerobic Baffled Reactor Technology

BSC-Ursa Minor 119

Abstract: Increased use of pharmaceuticals over recent decades have led to vast improvements in health in many locations across the globe. Pharmaceuticals and personal care products (PPCPs) enter the environment through human consumption and excretion, hospital waste discharges, improper disposal of medicine, and incomplete removal at municipal wastewater treatment plants. Once present in the environment, PPCPs interact with other compounds and are influenced by natural conditions, such as sunlight. Anaerobic baffled reactor (ABR) technology is a decentralized wastewater treatment system (DEWATS) implemented in locations across the globe and is being studied for its viability for urban and peri-urban communities in South Africa for non-potable reuse. Studies were conducted on ABR effluent to isolate the effects of sunlight on the concentration of a common HIV antiretroviral (ARV) chemical, zidovudine (AZT), known to have photoactive functional groups. Water quality parameters, including pH, temperature, dissolved oxygen (DO) concentration, and conductivity, were monitored in unspiked samples and samples spiked with AZT. Each sample was also solid-phase extracted for subsequent liquid chromatography analyses. Results indicate that water quality remained consistent through the experiment, which signifies that other factors, such as a change in pH or DO, did not influence the experiment, and any changes in AZT concentration would be due to solar radiation alone. UV/VIS absorbance intensities were also measured, and results, as compared to UV data from standards of known concentrations of AZT, showed a decrease in AZT over the five hours. These results will supplement further analyses via fluorescence spectrometry, high performance liquid chromatography (HPLC) and liquid chromatography mass spectrometry (LC-MS) to isolate the phototransformation effects on AZT in ABR effluent. Results from this experiment will inform further studies necessary to understand how PPCPs are transformed in the environment.

Keywords: Pharmaceuticals and Personal Care Products (PPCPs), Contaminants of Emerging Concern (CECs), Anaerobic Baffled Reactor (ABR), Decentralized Wastewater Treatment (DEWATS), zidovudine or azidothymidine (AZT), photodegradation, South Africa, water treatment, sustainability