Presentation Title

Synthesis of Magnetic Nanoparticles for Cardiovascular Applications

Faculty Mentor

Huinan Liu

Start Date

23-11-2019 8:00 AM

End Date

23-11-2019 8:45 AM

Location

159

Session

poster 1

Type of Presentation

Poster

Subject Area

engineering_computer_science

Abstract

Abstract

Synthesis of Magnetic Nanoparticles for Cardiovascular Applications

Gilberto Luis Peraza-Martinez1,2, Wayne Fook Leu1, Huinan Liu1

1Department of Bioengineering, University of California, Riverside

2Department of Electrical Engineering, University of California, Riverside

Cardiovascular diseases continue to plague people of all ages. Aortic stenosis, the narrowing of the aortic heart valve, is a cardiovascular disease that has a more relevant impact due to the longevity of our population. There are multiple choices in regard to treatment plans when dealing with the calcification of the aortic valve, which leads to aortic stenosis. Unfortunately, the design of many of these solutions also involves a greater risk associated with invasive surgeries. The design of the minimally invasive approach we are working on is based on the concept of using magnetic nanoparticles to guide a chelating agent to the calcium phosphate with the theory that it will break down into biodegradable materials that shall be absorbed by the body. The treatment nanoparticles were fabricated by the co-precipitation method, and these nanoparticles were studied using SEM. A flow device is used to study the treatment particles in a dynamic system.

Keywords: aortic stenosis, citric acid, iron oxide, calcification, flow device

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Nov 23rd, 8:00 AM Nov 23rd, 8:45 AM

Synthesis of Magnetic Nanoparticles for Cardiovascular Applications

159

Abstract

Synthesis of Magnetic Nanoparticles for Cardiovascular Applications

Gilberto Luis Peraza-Martinez1,2, Wayne Fook Leu1, Huinan Liu1

1Department of Bioengineering, University of California, Riverside

2Department of Electrical Engineering, University of California, Riverside

Cardiovascular diseases continue to plague people of all ages. Aortic stenosis, the narrowing of the aortic heart valve, is a cardiovascular disease that has a more relevant impact due to the longevity of our population. There are multiple choices in regard to treatment plans when dealing with the calcification of the aortic valve, which leads to aortic stenosis. Unfortunately, the design of many of these solutions also involves a greater risk associated with invasive surgeries. The design of the minimally invasive approach we are working on is based on the concept of using magnetic nanoparticles to guide a chelating agent to the calcium phosphate with the theory that it will break down into biodegradable materials that shall be absorbed by the body. The treatment nanoparticles were fabricated by the co-precipitation method, and these nanoparticles were studied using SEM. A flow device is used to study the treatment particles in a dynamic system.

Keywords: aortic stenosis, citric acid, iron oxide, calcification, flow device